{"id":2818,"date":"2025-06-03T09:36:15","date_gmt":"2025-06-03T09:36:15","guid":{"rendered":"https:\/\/www.entomon.it\/wordpress\/uso-terapeutico-del-veleno-dagli-insetti\/"},"modified":"2025-07-11T22:53:40","modified_gmt":"2025-07-11T22:53:40","slug":"therapeutic-use-of-insect-venom","status":"publish","type":"page","link":"https:\/\/www.entomon.it\/en\/therapeutic-use-of-insect-venom\/","title":{"rendered":"Therapeutic use of insect venom"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1352px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-flex-align-self-center fusion-animated\" style=\"--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:2.88%;--awb-width-medium:66.666666666667%;--awb-order-medium:0;--awb-spacing-right-medium:2.88%;--awb-spacing-left-medium:2.88%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInLeft\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-1 fusion-text-no-margin\" style=\"--awb-margin-bottom:15px;\"><h2>Overview of insect sting-related conditions and treatments.<\/h2>\n<\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;width:100%;max-width:90px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;--awb-sep-color:#ffbc00;border-color:#ffbc00;border-top-width:7px;\"><\/div><\/div><div class=\"fusion-text fusion-text-2 fusion-text-no-margin\" style=\"--awb-margin-top:25px;--awb-margin-bottom:0px;\"><p>Many insects represent a significant medical concern because their stings can cause serious conditions. Wasps and bees, in particular, are among the insects that most frequently interact with humans, and their venom can trigger allergic reactions of varying severity. The venom from these stings contains toxic molecules and allergens that the immune system recognizes as foreign, provoking a response that can range from localized reactions to more severe forms, such as <strong>anaphylactic shock<\/strong>.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-animated\" style=\"--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:5.76%;--awb-width-medium:33.333333333333%;--awb-order-medium:0;--awb-spacing-right-medium:5.76%;--awb-spacing-left-medium:5.76%;--awb-width-small:100%;--awb-order-small:0;--awb-margin-top-small:20px;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInUp\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element\" style=\"text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\" style=\"border-radius:8px;\"><img decoding=\"async\" width=\"450\" height=\"416\" alt=\"Macro image of a wasp stinging human skin\" title=\"Macro image of a wasp stinging human skin\" src=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Immagine-macro-di-una-vespa-nellatto-di-pungere-la-pelle-umana.jpg\" class=\"img-responsive wp-image-2641\" srcset=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Immagine-macro-di-una-vespa-nellatto-di-pungere-la-pelle-umana-200x185.jpg 200w, https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Immagine-macro-di-una-vespa-nellatto-di-pungere-la-pelle-umana-400x370.jpg 400w, https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Immagine-macro-di-una-vespa-nellatto-di-pungere-la-pelle-umana.jpg 450w\" sizes=\"(max-width: 640px) 100vw, 400px\" \/><\/span><\/div><div class=\"fusion-text fusion-text-3\" style=\"--awb-font-size:15px;--awb-margin-top:7px;--awb-margin-right:5px;--awb-margin-left:5px;\"><p>Macro image of a wasp stinging human skin<\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-margin-top:25px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1352px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-animated\" style=\"--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:5.76%;--awb-width-medium:33.333333333333%;--awb-order-medium:0;--awb-spacing-right-medium:5.76%;--awb-spacing-left-medium:5.76%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInLeft\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element\" style=\"--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-2 hover-type-none\" style=\"border-radius:8px;\"><img decoding=\"async\" width=\"450\" height=\"416\" alt=\"Allergic reaction after a bee, wasp, or hornet sting\" title=\"Allergic reaction after a bee, wasp, or hornet sting\" src=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Manifestazione-allergica-dopo-puntura-di-ape-vespa-o-calabrone.jpg\" class=\"img-responsive wp-image-2640\" srcset=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Manifestazione-allergica-dopo-puntura-di-ape-vespa-o-calabrone-200x185.jpg 200w, https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Manifestazione-allergica-dopo-puntura-di-ape-vespa-o-calabrone-400x370.jpg 400w, https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Manifestazione-allergica-dopo-puntura-di-ape-vespa-o-calabrone.jpg 450w\" sizes=\"(max-width: 640px) 100vw, 400px\" \/><\/span><\/div><div class=\"fusion-text fusion-text-4\" style=\"--awb-font-size:15px;--awb-margin-top:7px;--awb-margin-right:5px;--awb-margin-left:5px;\"><p>Case of allergic reaction after a bee, wasp, or hornet sting.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_2_3 2_3 fusion-flex-column fusion-animated\" style=\"--awb-padding-left:10px;--awb-bg-size:cover;--awb-width-large:66.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:2.88%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:2.88%;--awb-width-medium:66.666666666667%;--awb-order-medium:0;--awb-spacing-right-medium:2.88%;--awb-spacing-left-medium:2.88%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInRight\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-5 fusion-text-no-margin\" style=\"--awb-margin-bottom:15px;\"><h2>Allergic Reactions to Stings: What You Need to Know<\/h2>\n<\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;width:100%;max-width:90px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;--awb-sep-color:#ffbc00;border-color:#ffbc00;border-top-width:7px;\"><\/div><\/div><div class=\"fusion-text fusion-text-6\" style=\"--awb-margin-top:20px;\"><p>Allergic reactions to stings can vary significantly from person to person depending on individual predisposition. The most common symptoms include swelling, redness, and itching. In some cases, reactions can be more severe, affecting breathing and blood circulation, with potentially fatal outcomes if not treated promptly.<\/p>\n<\/div><div class=\"fusion-text fusion-text-7\" style=\"--awb-font-size:16px;\"><p>Clinical study published in the <em data-start=\"88\" data-end=\"145\">Journal of Allergy and Clinical Immunology: In Practice<\/em>: (in English)<br \/>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25841552\/\" target=\"_blank\" rel=\"noopener\">Anaphylaxis to Insect Stings: A Review of 1,000 Cases<\/a><\/p>\n<p>Fondazione Veronesi \u2013 <em>Popular science article on the use of desensitization vaccines against wasp and bee allergies.<\/em> (in Italian)<br \/>\n<a href=\"https:\/\/www.fondazioneveronesi.it\/magazine\/articoli\/pediatria\/vaccini-desensibilizzanti-contro-lallergia-a-vespe-e-api\" target=\"_blank\" rel=\"noopener\">Desensitization vaccines against wasp and bee allergies<\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-margin-top:25px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1352px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_3 1_3 fusion-flex-column fusion-animated\" style=\"--awb-bg-size:cover;--awb-width-large:33.333333333333%;--awb-margin-top-large:0px;--awb-spacing-right-large:5.76%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:5.76%;--awb-width-medium:33.333333333333%;--awb-order-medium:0;--awb-spacing-right-medium:5.76%;--awb-spacing-left-medium:5.76%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInLeft\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element\" style=\"--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-3 hover-type-none\" style=\"border-radius:8px;\"><img decoding=\"async\" width=\"450\" height=\"416\" alt=\"Administration of a vaccine for specific immunotherapy\" title=\"Administration of a vaccine for specific immunotherapy\" src=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Somministrazione-di-un-vaccino-per-limmunoterapia-allergica.jpg\" class=\"img-responsive wp-image-2639\" srcset=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Somministrazione-di-un-vaccino-per-limmunoterapia-allergica-200x185.jpg 200w, https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Somministrazione-di-un-vaccino-per-limmunoterapia-allergica-400x370.jpg 400w, https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/Somministrazione-di-un-vaccino-per-limmunoterapia-allergica.jpg 450w\" sizes=\"(max-width: 640px) 100vw, 400px\" \/><\/span><\/div><div class=\"fusion-text fusion-text-8\" style=\"--awb-font-size:15px;--awb-margin-top:7px;--awb-margin-right:5px;--awb-margin-left:5px;\"><p>Administration of a vaccine for allergy immunotherapy<\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_6 1_6 fusion-flex-column fusion-animated\" style=\"--awb-bg-size:cover;--awb-width-large:16.666666666667%;--awb-margin-top-large:0px;--awb-spacing-right-large:11.52%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:11.52%;--awb-width-medium:16.666666666667%;--awb-order-medium:0;--awb-spacing-right-medium:11.52%;--awb-spacing-left-medium:11.52%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInLeft\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-image-element\" style=\"text-align:center;--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-4 hover-type-none\" style=\"border-radius:8px;\"><img decoding=\"async\" width=\"242\" height=\"416\" alt=\"Flacone di vetro contenente veleno di vespa\" title=\"fiala-di-veleno-stratto-da-imenottero\" src=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/fiala-di-veleno-stratto-da-imenottero.jpg\" class=\"img-responsive wp-image-2638\" srcset=\"https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/fiala-di-veleno-stratto-da-imenottero-200x344.jpg 200w, https:\/\/www.entomon.it\/wordpress\/wp-content\/uploads\/2025\/06\/fiala-di-veleno-stratto-da-imenottero.jpg 242w\" sizes=\"(max-width: 640px) 100vw, 200px\" \/><\/span><\/div><div class=\"fusion-text fusion-text-9\" style=\"--awb-font-size:15px;--awb-margin-top:7px;--awb-margin-right:5px;--awb-margin-left:5px;\"><p>Glass vial of lyophilized venom extract, base for vaccine preparation<\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_2 1_2 fusion-flex-column fusion-animated\" style=\"--awb-padding-left:10px;--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:3.84%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:3.84%;--awb-width-medium:50%;--awb-order-medium:0;--awb-spacing-right-medium:3.84%;--awb-spacing-left-medium:3.84%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\" data-animationType=\"fadeInRight\" data-animationDuration=\"1.0\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-10 fusion-text-no-margin\" style=\"--awb-margin-bottom:15px;\"><h2 class=\"fusion-responsive-typography-calculated\" style=\"--fontsize: 29; line-height: 1.35;\" data-fontsize=\"29\" data-lineheight=\"39.15px\">Specific Immunotherapy (SIT): What It Is and How It Works<\/h2>\n<\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;width:100%;max-width:90px;\"><div class=\"fusion-separator-border sep-single sep-solid\" style=\"--awb-height:20px;--awb-amount:20px;--awb-sep-color:#ffbc00;border-color:#ffbc00;border-top-width:7px;\"><\/div><\/div><div class=\"fusion-text fusion-text-11\" style=\"--awb-margin-top:20px;\"><p>Specific Immunotherapy (SIT), or <b>Specific Allergen Immunotherapy<\/b>, is today one of the most effective medical practices to reduce allergic reactions in high-risk individuals. This therapy involves the preventive administration of controlled doses of the substances that trigger the allergic reaction, helping the immune system gradually tolerate the venom.<\/p>\n<p>Immunotherapy with purified venoms is currently the only therapeutic treatment that provides near-total protection in case of a new sting, with a success rate of 95\u201398% in treated cases.<\/p>\n<p>The immunotherapy treatment involves a regimen of gradually increasing venom doses until the protective dose is reached, usually 100 mcg. One of the most important features of immunotherapy is that protection lasts for years even after the treatment ends.<\/p>\n<p>The initial phase of the production process of these vaccines starts with the availability of the raw material consisting of insect venom. The purity of the venom is crucial as it directly affects the quality of the drug that will be prepared.<\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div style=\"text-align:center;\"><a class=\"fusion-button button-flat button-xlarge button-custom fusion-button-default button-1 fusion-button-span-no fusion-button-default-type\" style=\"--button_accent_color:#6b6b6b;--button_border_color:#6b6b6b;--button_accent_hover_color:#ffffff;--button_border_hover_color:#ffffff;--button_gradient_top_color:#e0e0e0;--button_gradient_bottom_color:#e0e0e0;--button_gradient_top_color_hover:#c4c4c4;--button_gradient_bottom_color_hover:#c4c4c4;\" target=\"_self\" href=\"https:\/\/www.entomon.it\/en\/products\/\"><span class=\"fusion-button-text awb-button__text awb-button__text--default\">SEE PRODUCTS<\/span><\/a><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"footnotes":""},"class_list":["post-2818","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - 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